DEFINING NEW THERAPEUTICS USING A MORE IMMUNOCOMPETENT MOUSE MODEL OF ANTIBODY-ENHANCED DENGUE VIRUS INFECTION

Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection

ABSTRACT With over 3.5 billion people at risk and approximately 390 million human infections per year, dengue virus (DENV) disease strains health care resources worldwide.Previously, we and others established models for DENV pathogenesis in mice that completely lack subunits of the receptors (Ifnar and Ifngr) for type I and type II interferon (IFN)

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Classification of Root Canal Configurations: A Review and a New Proposal of Nomenclature System for Root Canal Configuration

Pulp space is complex, root canals may divide and rejoin.In the simplest form each root with one canal Fall and single apical foramen is not observed always, other canal configurations are present which exit the root with two, three or more foramen.Several classifications have been proposed to describe root canal configurations for communication.Wi

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Prediction of Groundwater Arsenic Contamination using Geographic Information System and Artificial Neural Network

Ground water arsenic contamination is a well known health and environmental problem in Bangladesh.Sources of this heavy metal are known Flag to be geogenic, however, the processes of its release into groundwater are poorly understood phenomena.In quest of mitigation of the problem it is necessary to predict probable contamination before it causes a

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Fidel Castro - manager and marketologist of the revolution

The article is devoted to the problems of political leadership.Currently, the leaders of many countries in Europe, Asia and America claim to be the true leaders of their countries.As everyone knows, not everyone succeeds.The authors of this publication have attempted to determine the determinants and parameters of a successful manager of the late t

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